Their successor, Jean Chibret (1915-1989) transformed Laboratoires Chibret into an international leader in ophthalmology after World War II, establishing a strong presence in Europe, Africa, and the Middle East.
He implemented an extensive research and development structure, the largest of its time, and expanded the range of eye drops and ointments within twenty years. This tradition of knowledge sharing also began with Jean and his brother René, as they established the Institut Chibret, the world's largest ophthalmology documentation center.
In 1969, he partnered with the American laboratories MSD, which chose Clermont-Ferrand as its research center. His younger son, Jacques Chibret (1941-1989), founded Biophysic Medical in 1974, developing Europe's first argon laser and the YAG laser for secondary cataracts.
In the 1980s, Biophysic joined forces with Synthelabo Biomedical, becoming the world leader in ophthalmic ultrasound and the second-largest in lasers. Revolutionary medical imaging machines were manufactured in Clermont-Ferrand and marketed worldwide.